VOCs Characterisation and identification of volatile organic compounds in breath from patients and healthy controls

Airway inflammation causes an increased production of reactive oxygen species, responsible for degradation of cell membranes. During this process, volatile organic compounds (VOCs) are formed. Measurement of VOCs in exhaled breath of patients may therefore be useful for the assessment of airway inflammation. We are studying VOCs in all kinds of inflammatory conditions including for instance chronic obstructive pulmonary disease (COPD).

To reach our goals, We developed a methodological approach able to identify profiles of VOCs in breath unique for patient groups using GC-MS.

Associated Staff

Frederik-Jan van Schooten
Professor, Head of the department

Prof. dr. Frederik-Jan van Schooten Department of Pharmacology and Toxicology, NUTRIM School of Nutrition and Translational Research in Metabolism, more ...

Roger Godschalk
Associate Professor

Dr. Roger Godschalk graduated in Biological Health Sciences in 1995 at the Maastricht University (The Netherlands). He specialised in genetic toxicolo more ...

Agnes Boots
Assistant Professor

Upon obtaining my PhD degree end 2006, I have 16 years of experience in life sciences research in which I have published over 70 papers with an H-inde more ...

Agnieszka Smolinska
Assistant Professor

Agnieszka Smolinska studied Chemistry at the Faculty of Mathematics, Physic and Chemistry of the Silesian University in Katowice, Poland. Afterwards s more ...

Robert van Vorstenbosch
PhD Student

Robert van Vorstenbosch studied Forensic Science and Chemistry at the University of Amsterdam and VU University Amsterdam. During this period he perfo more ...