2016

  • Sharma UC,Mosleh W,Chaudhari MR,Katkar R,Weil B,Evelo C,Cimato TR,Pokharel S,Blankesteijn WM,Suzuki G Myocardial and Serum Galectin-3 Expression Dynamics Marks Post-Myocardial Infarction Cardiac Remodelling. Heart, lung & circulation; 2017 Jul 28094123,S1443-9506(16)31726-7,10.1016/j.hlc.2016.11.007,PMC5459666,NIHMS838257
  • Shi Q,Maas L,Veith C,Van Schooten FJ,Godschalk RW Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair. Archives of toxicology; 2017 Jun 28005143,10.1007/s00204-016-1907-4,10.1007/s00204-016-1907-4,PMC5429366
  • le Noble JL,Foudraine NA,Kornips FH,van Dam DG,Neef C,Janssen PK Extracorporeal Clearance of Levetiracetam During Continuous Venovenous Hemofiltration in a Critically Ill Patient and New Dosing Recommendation. Journal of clinical pharmacology; 2017 Apr 27868207,10.1002/jcph.844
  • Driessen JH,de Vries F,van Onzenoort H,Harvey NC,Neef C,van den Bergh JP,Vestergaard P,Henry RM The use of incretins and fractures - a meta-analysis on population-based real life data. British journal of clinical pharmacology; 2017 Apr 27780288,10.1111/bcp.13167,PMC5346876
  • Simons CC,Schouten LJ,Godschalk RW,van Engeland M,van den Brandt PA,van Schooten FJ,Weijenberg MP Energy restriction at young age, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk in the Netherlands Cohort Study. International journal of cancer; 2017 Jan 27649841,10.1002/ijc.30439
  • Tedjo DI,Smolinska A,Savelkoul PH,Masclee AA,van Schooten FJ,Pierik MJ,Penders J,Jonkers DM The fecal microbiota as a biomarker for disease activity in Crohn's disease. Scientific reports; 2016 Oct 27734914,srep35216,10.1038/srep35216,PMC5062155
  • Hogervorst JG,van den Brandt PA,Godschalk RW,van Schooten FJ,Schouten LJ The influence of single nucleotide polymorphisms on the association between dietary acrylamide intake and endometrial cancer risk. Scientific reports; 2016 Oct 27713515,srep34902,10.1038/srep34902,PMC5054678
  • Sthijns MM,Weseler AR,Bast A,Haenen GR Time in Redox Adaptation Processes: From Evolution to Hormesis. International journal of molecular sciences; 2016 Sep 27690013,ijms17101649,10.3390/ijms17101649,PMC5085682
  • Deckers IA,van den Brandt PA,van Engeland M,van Schooten FJ,Godschalk RW,Keszei AP,Hogervorst JG,Schouten LJ Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer. Scientific reports; 2016 Sep 27686058,PMC5043233,srep34262,10.1038/srep34262
  • Guédon A,Rome A,Deville JL,Besse M,Blanchet L,Savry A,Gauthier-Villano L,Bertault-Peres P,Pourroy B Computerized Provider Order Entry Using Two Prescription-Writing Software in Oncology. American journal of medical quality : the official journal of the American College of Medical Quality; 27565815,1062860616666164,10.1177/1062860616666164
  • Drent M,Bast A,Bootsma HP,Deneer V Repositioning 'old' drugs to treat rare diseases: arguing from the mechanism of action. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG; 2016 Aug 27537726
  • van Kuijk SJ,Gieling RG,Niemans R,Lieuwes NG,Biemans R,Telfer BA,Haenen GR,Yaromina A,Lambin P,Dubois LJ,Williams KJ The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PloS one; 2016 27513947,10.1371/journal.pone.0161040,PONE-D-16-20254,PMC4981362
  • Janssen PK,Foudraine NA,Burgers DM,Neef K,le Noble JL Population Pharmacokinetics of Cefuroxime in Critically Ill Patients Receiving Continuous Venovenous Hemofiltration With Regional Citrate Anticoagulation and a Phosphate-Containing Replacement Fluid. Therapeutic drug monitoring; 2016 Dec 27494946,10.1097/FTD.0000000000000330
  • Snowden KC,Janssen BJ Structural biology: Signal locked in. Nature; 2016 08 27479322,nature19418,10.1038/nature19418
  • van Leusden P,den Hartog GJ,Bast A,Postema M,van der Linden E,Sagis LM Structure engineering of filled protein microbeads to tailor release of oil droplets in gastric digestion. Food & function; 2016 Aug 27458022,10.1039/c6fo00405a
  • Kong Y,Janssen BJ,Malinauskas T,Vangoor VR,Coles CH,Kaufmann R,Ni T,Gilbert RJ,Padilla-Parra S,Pasterkamp RJ,Jones EY Structural Basis for Plexin Activation and Regulation. Neuron; 2016 Aug 27397516,S0896-6273(16)30295-1,10.1016/j.neuron.2016.06.018,PMC4980550
  • Wei FF,Zhang ZY,Petit T,Cauwenberghs N,Gu YM,Thijs L,Raaijmakers A,Jacobs L,Yang WY,Allegaert K,Kuznetsova T,Verhamme P,Struijker-Boudier HA,Li Y,Asayama K,Staessen JA Retinal microvascular diameter, a hypertension-related trait, in ECG-gated vs. non-gated images analyzed by IVAN and SIVA. Hypertension research : official journal of the Japanese Society of Hypertension; 2016 Dec 27383509,hr201681,10.1038/hr.2016.81
  • Wei FF,Zhang ZY,Thijs L,Yang WY,Jacobs L,Cauwenberghs N,Gu YM,Kuznetsova T,Allegaert K,Verhamme P,Li Y,Struijker-Boudier HA,Staessen JA Conventional and Ambulatory Blood Pressure as Predictors of Retinal Arteriolar Narrowing. Hypertension (Dallas, Tex. : 1979); 2016 Aug 27324224,HYPERTENSIONAHA.116.07523,10.1161/HYPERTENSIONAHA.116.07523,PMC4956676
  • Godschalk RW,Vanhees K,Maas L,Drittij MJ,Pachen D,van Doorn-Khosrovani Sv,van Schooten FJ,Haenen GR Does Ataxia Telangiectasia Mutated (ATM) protect testicular and germ cell DNA integrity by regulating the redox status? Reproductive toxicology (Elmsford, N.Y.); 2016 Aug 27318254,S0890-6238(16)30147-2,10.1016/j.reprotox.2016.06.008
  • Daeichin V,Kooiman K,Skachkov I,Bosch JG,Theelen TL,Steiger K,Needles A,Janssen BJ,Daemen MJ,van der Steen AF,de Jong N,Sluimer JC Quantification of Endothelial αvβ3 Expression with High-Frequency Ultrasound and Targeted Microbubbles: In Vitro and In Vivo Studies. Ultrasound in medicine & biology; 2016 Sep 27302657,S0301-5629(16)30062-X,10.1016/j.ultrasmedbio.2016.05.005
  • Jongen AC,Bosmans JW,Kartal S,Lubbers T,Sosef M,Slooter GD,Stoot JH,van Schooten FJ,Bouvy ND,Derikx JP Predictive Factors for Anastomotic Leakage After Colorectal Surgery: Study Protocol for a Prospective Observational Study (REVEAL Study). JMIR research protocols; 2016 Jun 27282451,v5i2e90,10.2196/resprot.5477,PMC4919551
  • Bolze F,Bast A,Mocek S,Morath V,Yuan D,Rink N,Schlapschy M,Zimmermann A,Heikenwalder M,Skerra A,Klingenspor M Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation. Diabetologia; 2016 Sep 27272237,10.1007/s00125-016-4004-6,10.1007/s00125-016-4004-6
  • Altara R,Manca M,Hessel MH,Gu Y,van Vark LC,Akkerhuis KM,Staessen JA,Struijker-Boudier HA,Booz GW,Blankesteijn WM CXCL10 Is a Circulating Inflammatory Marker in Patients with Advanced Heart Failure: a Pilot Study. Journal of cardiovascular translational research; 2016 Aug 27271043,10.1007/s12265-016-9703-3,10.1007/s12265-016-9703-3
  • Mujagic Z,Tigchelaar EF,Zhernakova A,Ludwig T,Ramiro-Garcia J,Baranska A,Swertz MA,Masclee AA,Wijmenga C,van Schooten FJ,Smolinska A,Jonkers DM A novel biomarker panel for irritable bowel syndrome and the application in the general population. Scientific reports; 2016 Jun 27263852,srep26420,10.1038/srep26420,PMC4893613
  • van der Wurff IS,Bakker EC,Hornstra G,Kirschner PA,Gielen M,Godschalk RW,Kremers S,Zeegers MP,de Groot RH Association between prenatal and current exposure to selected LCPUFAs and school performance at age 7. Prostaglandins, leukotrienes, and essential fatty acids; 2016 05 27154361,S0952-3278(15)30014-4,10.1016/j.plefa.2016.03.005
  • Baranska A,Mujagic Z,Smolinska A,Dallinga JW,Jonkers DM,Tigchelaar EF,Dekens J,Zhernakova A,Ludwig T,Masclee AA,Wijmenga C,van Schooten FJ Volatile organic compounds in breath as markers for irritable bowel syndrome: a metabolomic approach. Alimentary pharmacology & therapeutics; 2016 Jul 27136066,10.1111/apt.13654
  • van Osch FH,Jochems SH,van Schooten FJ,Bryan RT,Zeegers MP Quantified relations between exposure to tobacco smoking and bladder cancer risk: a meta-analysis of 89 observational studies. International journal of epidemiology; 2016 Jun 27097748,dyw044,10.1093/ije/dyw044
  • van Gisbergen MW,Cebula M,Zhang J,Ottosson-Wadlund A,Dubois L,Lambin P,Tew KD,Townsend DM,Haenen GR,Drittij-Reijnders MJ,Saneyoshi H,Araki M,Shishido Y,Ito Y,Arnér ES,Abe H,Morgenstern R,Johansson K Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Molecular pharmaceutics; 2016 06 27093577,10.1021/acs.molpharmaceut.6b00140,PMC5241094,NIHMS834360
  • Vrolijk MF,Opperhuizen A,Jansen EH,Bast A,Haenen GR Iron Supplements and Magnesium Peroxide: An Example of a Hazardous Combination in Self-Medication. Basic & clinical pharmacology & toxicology; 2016 Oct 27061346,10.1111/bcpt.12603
  • Pijls KE,Jonkers DM,Elizalde M,Drittij-Reijnders MJ,Haenen GR,Bast A,Masclee AA,Koek GH Is intestinal oxidative stress involved in patients with compensated liver cirrhosis? Annals of hepatology; 27049494,1198816,10.5604/16652681.1198816
  • Heyninck K,Sabbe L,Chirumamilla CS,Szarc Vel Szic K,Vander Veken P,Lemmens KJ,Lahtela-Kakkonen M,Naulaerts S,Op de Beeck K,Laukens K,Van Camp G,Weseler AR,Bast A,Haenen GR,Haegeman G,Vanden Berghe W Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway. Biochemical pharmacology; 2016 Jun 27045103,S0006-2952(16)30022-3,10.1016/j.bcp.2016.03.026
  • Roksnoer LC,Heijnen BF,Nakano D,Peti-Peterdi J,Walsh SB,Garrelds IM,van Gool JM,Zietse R,Struijker-Boudier HA,Hoorn EJ,Danser AH On the Origin of Urinary Renin: A Translational Approach. Hypertension (Dallas, Tex. : 1979); 2016 May 26928805,HYPERTENSIONAHA.115.07012,10.1161/HYPERTENSIONAHA.115.07012,PMC4833618,NIHMS759073
  • Kaminskyy D,den Hartog GJM,Wojtyra M,Lelyukh M,Gzella A,Bast A,Lesyk R Antifibrotic and anticancer action of 5-ene amino/iminothiazolidinones. European journal of medicinal chemistry; 2016 Apr 26896707,S0223-5234(16)30081-2,10.1016/j.ejmech.2016.02.011
  • Van Vliet D,Smolinska A,Jöbsis Q,Rosias PP,Muris JW,Dallinga JW,van Schooten FJ,Dompeling E Association between exhaled inflammatory markers and asthma control in children. Journal of breath research; 2016 Feb 26893372,10.1088/1752-7155/10/1/016014
  • Ruijters EJ,Haenen GR,Willemsen M,Weseler AR,Bast A Food-Derived Bioactives Can Protect the Anti-Inflammatory Activity of Cortisol with Antioxidant-Dependent and -Independent Mechanisms. International journal of molecular sciences; 2016 Feb 26891295,ijms17020239,10.3390/ijms17020239,PMC4783970
  • Schleich FN,Dallinga JW,Henket M,Wouters EF,Louis R,Van Schooten FJ Volatile organic compounds discriminate between eosinophilic and neutrophilic inflammation in vitro. Journal of breath research; 2016 Feb 26828318,10.1088/1752-7155/10/1/016006
  • Pijls KE,Smolinska A,Jonkers DM,Dallinga JW,Masclee AA,Koek GH,van Schooten FJ A profile of volatile organic compounds in exhaled air as a potential non-invasive biomarker for liver cirrhosis. Scientific reports; 2016 Jan 26822454,srep19903,10.1038/srep19903,PMC4731784
  • Lefel N,Janssen L,le Noble J,Foudraine N Sodium bicarbonate prophylactic therapy in the prevention of contrast-induced nephropathy in patients admitted to the intensive care unit of a teaching hospital: a retrospective cohort study. Journal of intensive care; 2016 26759720,10.1186/s40560-016-0127-6,127,PMC4710042
  • Marsch E,Theelen TL,Janssen BJ,Briede JJ,Haenen GR,Senden JM,van Loon LJ,Poeze M,Bierau J,Gijbels MJ,Daemen MJ,Sluimer JC The effect of prolonged dietary nitrate supplementation on atherosclerosis development. Atherosclerosis; 2016 Feb 26724532,S0021-9150(15)30227-6,10.1016/j.atherosclerosis.2015.11.031
  • Pedersen M,Mendez MA,Schoket B,Godschalk RW,Espinosa A,Landström A,Villanueva CM,Merlo DF,Fthenou E,Gracia-Lavedan E,van Schooten FJ,Hoek G,Brunborg G,Meltzer HM,Alexander J,Nielsen JK,Sunyer J,Wright J,Kovács K,de Hoogh K,Gutzkow KB,Hardie LJ,Chatzi L,Knudsen LE,Anna L,Ketzel M,Haugen M,Botsivali M,Nieuwenhuijsen MJ,Cirach M,Toledano MB,Smith RB,Fleming S,Agramunt S,Kyrtopoulos SA,Lukács V,Kleinjans JC,Segerbäck D,Kogevinas M Erratum: "Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris)". Environmental health perspectives; 2016 Jan 26720407,10.1289/ehp.124-A12,PMC4710585
  • Maessen DE,Brouwers O,Gaens KH,Wouters K,Cleutjens JP,Janssen BJ,Miyata T,Stehouwer CD,Schalkwijk CG Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. Diabetes; 2016 Apr 26718500,db15-1390,10.2337/db15-1390
  • Hermans KC,Daskalopoulos EP,Blankesteijn WM The Janus face of myofibroblasts in the remodeling heart. Journal of molecular and cellular cardiology; 2016 Feb 26690324,S0022-2828(15)30121-8,10.1016/j.yjmcc.2015.11.017
  • Paulis L,Foulquier S,Namsolleck P,Recarti C,Steckelings UM,Unger T Combined Angiotensin Receptor Modulation in the Management of Cardio-Metabolic Disorders. Drugs; 2016 Jan 26631237,10.1007/s40265-015-0509-4,10.1007/s40265-015-0509-4,PMC4700059
  • Yu Y,Teerenstra S,Neef C,Burger D,Maliepaard M A comparison of the intrasubject variation in drug exposure between generic and brand-name drugs: a retrospective analysis of replicate design trials. British journal of clinical pharmacology; 2016 Apr 26574160,10.1111/bcp.12828,PMC4799932
  • Gu YM,Petit T,Wei FF,Thijs L,Jacobs L,Zhang ZY,Yang WY,Cauwenberghs N,Knez J,Struijker-Boudier HA,Kuznetsova T,Verhamme P,Staessen JA Renal glomerular dysfunction in relation to retinal arteriolar narrowing and high pulse pressure in seniors. Hypertension research : official journal of the Japanese Society of Hypertension; 2016 Mar 26559607,hr2015125,10.1038/hr.2015.125
  • Knapen LM,van Dalem J,Keulemans YC,van Erp NP,Bazelier MT,De Bruin ML,Leufkens HG,Croes S,Neef C,de Vries F,Driessen JH Use of incretin agents and risk of pancreatic cancer: a population-based cohort study. Diabetes, obesity & metabolism; 2016 Mar 26537555,10.1111/dom.12605
  • van Osch FH,Jochems SH,van Schooten FJ,Bryan RT,Zeegers MP Significant Role of Lifetime Cigarette Smoking in Worsening Bladder Cancer and Upper Tract Urothelial Carcinoma Prognosis: A Meta-Analysis. The Journal of urology; 2016 Apr 26523878,S0022-5347(15)05162-9,10.1016/j.juro.2015.10.139
  • Blanchet L,Smolinska A Data Fusion in Metabolomics and Proteomics for Biomarker Discovery. Methods in molecular biology (Clifton, N.J.); 2016 26519180,10.1007/978-1-4939-3106-4_14
  • Bolze F,Morath V,Bast A,Rink N,Schlapschy M,Mocek S,Skerra A,Klingenspor M Long-Acting PASylated Leptin Ameliorates Obesity by Promoting Satiety and Preventing Hypometabolism in Leptin-Deficient Lep(ob/ob) Mice. Endocrinology; 2016 Jan 26492472,10.1210/en.2015-1519
  • Randall MJ,Haenen GR,Bouwman FG,van der Vliet A,Bast A The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase. Toxicology letters; 2016 Jan 26481333,S0378-4274(15)30073-4,10.1016/j.toxlet.2015.10.009,PMC4725588,NIHMS746839
  • Boggia J,Luzardo L,Lujambio I,Sottolano M,Robaina S,Thijs L,Olascoaga A,Noboa O,Struijker-Boudier HA,Safar ME,Staessen JA The Diurnal Profile of Central Hemodynamics in a General Uruguayan Population. American journal of hypertension; 2016 Jun 26476084,hpv169,10.1093/ajh/hpv169
  • Shi Q,Haenen GR,Maas L,Arlt VM,Spina D,Vasquez YR,Moonen E,Veith C,Van Schooten FJ,Godschalk RW Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene. Archives of toxicology; 2016 Sep 26438400,10.1007/s00204-015-1593-7,10.1007/s00204-015-1593-7,PMC4982897
  • Haeseker M,Croes S,Neef C,Bruggeman C,Stolk L,Verbon A Evaluation of Vancomycin Prediction Methods Based on Estimated Creatinine Clearance or Trough Levels. Therapeutic drug monitoring; 2016 Feb 26418699,10.1097/FTD.0000000000000250
  • Manjeri GR,Rodenburg RJ,Blanchet L,Roelofs S,Nijtmans LG,Smeitink JA,Driessen JJ,Koopman WJ,Willems PH Increased mitochondrial ATP production capacity in brain of healthy mice and a mouse model of isolated complex I deficiency after isoflurane anesthesia. Journal of inherited metabolic disease; 2016 Jan 26310962,10.1007/s10545-015-9885-x,10.1007/s10545-015-9885-x,PMC4710641
  • Rutten EP,Gopal P,Wouters EF,Franssen FM,Hageman GJ,Vanfleteren LE,Spruit MA,Reynaert NL Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD. Chest; 2016 Jan 26066545,S0012-3692(15)00125-7,10.1378/chest.15-0645
  • Krais AM,Speksnijder EN,Melis JP,Indra R,Moserova M,Godschalk RW,van Schooten FJ,Seidel A,Kopka K,Schmeiser HH,Stiborova M,Phillips DH,Luijten M,Arlt VM The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Archives of toxicology; 2016 Apr 25995008,10.1007/s00204-015-1531-8,10.1007/s00204-015-1531-8,PMC4785204