Department of Pharmacology & Toxicology

VOCs Characterisation and identification of volatile organic compounds in breath from patients and healthy controls

Airway inflammation causes an increased production of reactive oxygen species, responsible for degradation of cell membranes. During this process, volatile organic compounds (VOCs) are formed. Measurement of VOCs in exhaled breath of patients may therefore be useful for the assessment of airway inflammation. We are studying VOCs in all kinds of inflammatory conditions including for instance chronic obstructive pulmonary disease (COPD).

To reach our goals, We developed a methodological approach able to identify profiles of VOCs in breath unique for patient groups using GC-MS.

Associated Staff

Roger Godschalk
Assistant Professor

​Dr. Roger Godschalk graduated in Biological Health Sciences in 1995 at the Maastricht University (The Netherlands). He specialised in genetic toxicol more ...

Frederik-Jan van Schooten
Professor, Head of the department

​Prof. van Schooten studied biology at the Free University of Amsterdam, The Netherlands, where he specialised in immunology, molecular microbiology a more ...

Jan Dallinga
Assistant Professor

​Jan Dallinga studied chemistry at the University of Groningen, The Netherlands, where he specialised in Physical-Organic Chemistry and graduated in 1 more ...

Agnes Boots
Assistant Professor

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Agnieszka Smolinska
Postdoctoral Fellow

Agnieszka Smolinska studied Chemistry at the Faculty of Mathematics, Physic and Chemistry of the Silesian University in Katowice, Poland. Afterwards s more ...

Rianne Fijten
PhD Student

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Charlotte Pauwels
PhD Student

​Charlotte Pauwels was born on April 6th 1990 in Duffel, Belgium. In 2008, she started her study Biomedical Sciences at the Radboud University, Nijmeg more ...

Agnieszka Baranska
PhD Student

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Edwin Moonen
Former Staff

​Edwin Moonen has studied on the technical school for chemistry in Heerlen, and is specialised in analytical chemistry and instrumental techniques. Fr more ...

Lionel Blanchet
Former Staff

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